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REAL WORLD IMPACT:
EMLy-optimised TCR-NK candidate developed by Zelluna is advancing to
the clinic

AI built for faster biologics discovery

Decode, predict, and design development-ready therapeutic candidates through a simple conversational interface

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OUR MISSION

Biologics discovery needs more than generic AI

AI-guided design holds enormous promise for accelerating development pipelines. However, most models are not designed to address the developability, manufacturability, or stability issues behind most drug candidate failures.

 

Built by the scientists behind 20+ FDA-approved therapies, EMLy Co-pilot addresses this gap.

Compress discovery from weeks to minute

EMLy helps you move faster by orchestrating models, datasets, and computational resources so you can focus on your science.

Turn conversation into actionable science

Through a simple yet scientifically fluent chat interface, EMLy transforms your questions into high-impact, design-ready outputs.

Built to adapt to real therapeutic challenges

Grounded in rich immunological data and experimental validation, EMLy can help you explore multiple modalities (mAbs, TCRs, and more!)

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OUR PLATFORM

EMLy Co-pilot: one interface, many capabilities.

EMLy Co-pilot is an integrated AI platform that unifies biologics design workflows, previously requiring dozens of bioinformatics and computational tools, into a single, conversational experience.

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The Co-pilot experience

Go from conversation to candidate in minutes

Your time is valuable. Spend it on the science that counts, while the co-pilot tackles the tedious, manual work:
 

  • Finding and manipulating structural models

  • Creating and evaluating variants 

  • Designing candidate libraries 

  • Streamlining cloning workflows

Underpinned by powerful, validated computational capabilities

Proprietary

structural modeling

Evaluate structural elements associated with therapeutic function and efficacy

Variant

generation

Enables iterative thinking and design branching to produce variants in minutes

Biologics
optimization

Engineers molecules for improved stability, expression, and manufacturability

Machine learning
model development

Scans through immune datasets to learn the ‘language’ of effective immune motifs

Explore EMLy co-pilot
Explore custom projects

OUR MISSION

Pioneer the combination of machine and human intelligence to develop the best immunotherapies for cancer patients in urgent need

3

TCR and Antibody specific LLMs fine-tuned/created

3

Pipeline programmes

6

In silico design to lead candidates in six months

HOW CAN WE HELP YOU?

Elevate your drug discovery outcomes.
 

We deliver safer, more precise drug candidates for your pipeline – faster.

How it works

Rapid design & engineering of new candidates and biobetters

Unlock the full potential of your research with EMLy Co-pilot & LLMs

Industry-first TCR and antibody-specific LLMs connected to EMLy co-pilot, empowering scientists with cutting-edge informatics & insights.

Discover how we identify novel targets and therapeutics through the Long term Cancer Survivor Program

Leverage our unmatched scale in deep sequencing, enhanced by EMLy AI error correction, to boost immune repertoire accuracy and align with our exclusive proprietary databases.

 

Discover how we identify our next target through the Long Term Survivor Programme.

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OUR TECHNOLOGY

Introducing EMLy™ 
The world’s leading repertoire decoding technology specifically built for TCR, Antibodies & Bi-Specifics.

A multi-modality platform

EMLy’s protein language models are designed to be both modality- and disease-agnostic. As solution architects, we recognise that there is no one-size-fits-all approach to protein design—each solution is uniquely tailored to meet specific therapeutic needs.

TCR
Antibody
Bispecific
VHH

OUR STUDY

The Long-term Cancer Survivor Study

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Cancer patients cured by immunotherapies hold the key to curing other patients in their immune repertoire 

 

We are investigating the immune repertoire of long-term cancer survivors to uncover novel TCRs, antibodies and targets

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Samples

We can access blood and tumour samples, directly or via University of Surrey.

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Sequencing

We can deep sequence immune sequence immune repertoires and have databases of 1bn TCRs and 2bn antibodies.

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Analysis

We can analyse repertoires with our proprietary LLMs.

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Engineering

We can engineer TCRs & antibodies into immune engagers.

INTRODUCING CO-PILOT

Your partner in AI driven drug discovery

Our groundbreaking work

Long term cancer survivor study

ETC-101 Oncology PRAME

ETC-201 Oncology First-in-Class

OUR PARTNERS

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AS SEEN IN

ETCEMBLY PROGRAMS

OUR CASE STUDIES

At the forefront of innovation

1

Affinity optimisation

2

Stability and developability

Affinity optimisation

EMLy™ can take TCR/

antibody sequences

and predict affinity

matured variants

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Protocol driven molecular docking

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...to explore the
complex conformational phase space  

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High throughput screen of protein variants

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Evaluation of

dynamic interactions

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Top 50 hit candidate variants selected for validation testing

stability and developability

With EMLy you can

supercharge stability

and developability

of your asset

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Combining alpha
& beta mutations results in a 20-fold increased expression yield

Join us in our journey as we explore how Etcembly is transforming the landscape of drug discovery with AI-driven solutions.

Feel free to download our
printable information sheet.

This document is password protected. Please complete the contact form and we'll email you the password.

Information sheet request

You can change your mind at any time by clicking the unsubscribe link in the footer of any email you receive from us.


Join us in our journey as we explore how Etcembly is transforming the landscape of drug discovery with AI-driven solutions.

Feel free to download a printable version of our information sheet here. This document is password protected. Please complete the contact form and we'll email you the password.

Information sheet request

You can change your mind at any time by clicking the unsubscribe link in the footer of any email you receive from us.


OUR MOTIVATION

For teams building the next generation of biologics

From nimble seed-stage biotechs to global R&D organizations, EMLy gives scientists access to advanced AI-driven biologics discovery, without requiring specialized computational expertise.

Preclinical

Lead

optimization

& CMC

Hit-to-lead

Target -to-hit

Target hypothesis

Custom workflow:

Proprietry immune sequencing.

Co-pilot

Custom workflow:

Immune repertoire analysis.

Small molecule design.

Co-complex prediction.

Custom workflow:

Antibody expression enhancement.

OUR TEAM

Developed by scientists

Our technology is built by our scientists, who are behind 20+ FDA-approved therapies. We are committed to developing the next generation of scientists and welcome motivated individuals who share our vision. If you aspire to break boundaries in precision medicine and are able to demonstrate understanding in the convergence of these fields, we are interested in hearing from you.

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Michelle Teng

CEO

Co-founder​

20 years of experience across pipeline from discovery to translational medicine in Immunocore (KIMMTRAK) & AstraZeneca (FluMist)

 

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Jacob Hurst

CTO

Co-founder​

25 years of experience in translational medicine (KIMMTRAK), TCR and antibody repertoire analytics (Abysis)

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NICK PUMPHREY

CSO

Over 20 years of experience developing TCR-based therapeutics at Immunocore and Adaptimmune (Afamicel)

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MITHI THAYA

Tech Advisor

Experienced tech

founder with multiple

successful exits

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JOHN MCCAFFERTY

Scientific Advisor

Serial entrepreneur.

Founder of Cambridge

Antibody Technology,

Maxion Tx, IonTas

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NICK CROSS

Chairman

Serial founder and investor

with considerable Board

experience, including

Immunocore,

Adaptimmune, Oxford

Asymmetry and Oxford

Semiconductor Ltd

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Bent Jakobsen

Director

TCR therapies pioneer.

Founded Immunocore

and Adaptimmune

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OUR INVITATION

Ready to research smarter and discover faster?

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